Isotopically Labeled Compounds
Cayman Chemical AbIrateron Acetate-d4 10mg
An internal standard for the quantification of abiraterone acetate by GC- or LC-MS
Cambridge Isotope Laboratories Modified JIS PCB Sampling Spike (13C12 99%) 1 2 mL
Modified JIS PCB Sampling Spike (13C12 99%) 1 2 mL
Medchemexpress LLC Propazine-d14 | 1219802-87-5 | 99.0% | 5 MG
Propazine-d14 is a deuterium labeled Propazine, intended for research use only. It can serve as a tracer or an internal standard for quantitative analysis in various analytical techniques such as NMR, GC-MS, or LC-MS. Stable heavy isotopes like deuterium are incorporated into drug molecules primarily for quantitation during drug development and can also influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Acts as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes to aid in drug development.
- Potential to affect pharmacokinetic and metabolic profiles of drugs.
Cayman Chemical GlycohyocholIc AcId-d4 1mg
An internal standard for the quantification of glycohyocholic acid by GC- or LC-MS
Medchemexpress LLC Pacritinib-d4 | 476.60 | 5 MG
Pacritinib-d4 (SB1518-d4) is the deuterium labeled Pacritinib. It is a potent inhibitor of both wild-type JAK2 (IC50=23 nM) and JAK2V617F mutant (IC50=19 nM). This compound also inhibits FLT3 (IC50=22 nM) and its mutant FLT3D835Y (IC50=6 nM). Stable heavy isotopes have been incorporated into drug molecules, primarily as tracers for quantitation during the drug development process. Deuteration has garnered attention due to its potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled compound
- Potent inhibitor of wild-type JAK2 and JAK2V617F mutant
- Inhibits FLT3 and its mutant FLT3D835Y
- Used as a tracer for quantitation during drug development
- Potential to affect pharmacokinetic and metabolic profiles
Medchemexpress LLC D-Sorbitol-d8 | 287962-59-8 | 98.9% | 1 MG
D-Sorbitol-d8 is a deuterium-labeled version of D-Sorbitol, a six-carbon sugar alcohol. D-Sorbitol can be used as a sugar substitute, stabilizing excipient, isotonicity agent, sweetener, humectant, thickener, and dietary supplement. This product is intended for research use only.
- Used as a tracer
- Can be used as an internal standard for quantitative analysis
- Functions as a stabilizing excipient
- Acts as an isotonicity agent
- Serves as a sweetener
- Used as a humectant
- Functions as a thickener
- Can be used as a dietary supplement
Medchemexpress LLC GW2580-d6 | 2733770-48-2 | 98.4% | 372.45 | 10 MG
GW2580-d6 is the deuterium labeled GW2580, an orally bioavailable and selective inhibitor of c-Fms kinase. It completely inhibits human cFMS kinase in vitro at 0.06 μM by competitively inhibiting ATP binding and suppressing colony-stimulating-factor-1 signaling. It is suitable for use as a tracer and an internal standard for quantitative analysis in various analytical methods.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes incorporated into drug molecules largely serve as tracers for quantitation during drug development
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs
Cambridge Isotope Laboratories N-BUTANOL (D9, 98%), 5 G, 25493-17-8
N-BUTANOL (D9, 98%), 5 G, 25493-17-8
Cambridge Isotope Laboratories Sodium pyruvate (1-13C 99%) 0 25 g
Sodium pyruvate (1-13C 99%) 0 25 g
Cambridge Isotope Laboratories PROPIONIC ACID (2,2-D2, 98%), 5 G, 19136-91-5
PROPIONIC ACID (2,2-D2, 98%), 5 G, 19136-91-5
Medchemexpress LLC Citric acid-2,4-13C2 | 121633-50-9 | MFCD00143997 | 98.0% | 194.11 | C4(13C)2H8O7 | 10 MG
Citric acid-2,4-13C2 is a stable-isotope labeled form of citric acid with two 13C atoms incorporated at positions 2 and 4. It is provided as a small-quantity, research-grade material for analytical and biochemical applications, and is commonly used where isotopic tracing or internal standardization is required for quantitative methods.
- Stable 13C labeling at positions 2 and 4.
- Suitable as a tracer or internal standard for NMR, GC-MS, and LC-MS.
- High chemical purity for quantitative analysis.
- Supplied in laboratory-scale vial sizes for ease of use.
- Enables metabolic tracing and isotope-dilution experiments.
Medchemexpress LLC Sphingosine-1-phosphate | 26993-30-6 | 99.5% | 379.47 | 50 MG
Sphingosine-1-phosphate (S1P) acts as an agonist for S1P1-5 receptors and serves as a ligand for GPR3, GPR6, and GPR12. It functions as an intracellular second messenger and triggers Ca2+ mobilization as an extracellular ligand for G protein-coupled receptors. S1P is a crucial lipid mediator derived from Sphingomyelin or other membrane phospholipids.
- Promotes DNA synthesis.
- Promotes cell proliferation.
- Promotes migration.
- Acts as an intracellular second messenger.
- Triggers Ca2+ mobilization.
Medchemexpress LLC Ceftriaxone-d3 disodium | 1132650-38-4 | 96.6% | 1 MG
Ceftriaxone-d3 (disodium) is the deuterium labeled version of Ceftriaxone, a third-generation cephalosporin antibiotic effective against many gram-negative and most gram-positive microorganisms. It also exhibits anti-inflammatory and antioxidant characteristics. Stable heavy isotopes, such as deuterium, are incorporated into drug molecules to act as tracers for quantitation during drug development, and deuteration can influence the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Cayman Chemical SpIroxamIn-d4 1mg
An internal standard for the quantification of spiroxamine by GC- or LC-MS